Sentence examples for a secondary decrease in from inspiring English sources

As an alternative hypothesis it has been proposed that decreased HBV replication by limiting HSP60 release from infected hepatocytes, results in a secondary decrease in the frequency of CD4 T cells with regulatory/suppressor capacity (Tregs).

Immediately upon standing, the reduction in blood pressure is accompanied by (1) an initial increase in peripheral vascular resistance, either as part of baroreflex-mediated sympathetic activation or secondary to passive changes in vessel calibre, and (2) a secondary decrease in resistance approximately 10 s after the initial onset of hypotension (Olufsen et al. 2002).

An indirect effect of 1,25(OH 2D3 on bone resorption mediated by reduction of inflammation resulting in a secondary decrease of bone resorption can be excluded as a cause for this observation, because 1,25(OhasD3 has clearly no suppressive effect on inflammation in our treatment protocol.

Although the exact underlying mechanisms remain unclear, the proliferation, apoptosis, and invasion of MMH-RT and HCC cells could be regulated by both blockade of aPKC ι signal pathway and the secondary decrease in aPKC ι.

These responses are often characterized by primary decreases in important indices of cardiac and thermoregulatory function, along with secondary decreases in associated parameters.

Inspection of rat upper maxilla treated with tacrolimus (1 mg/kg/day) for 60 days demonstrated an increase in alveolar bone volume secondary to a decrease in osteoclast number compared to rats treated with a drug vehicle [ 22].

These results suggest that the ability of ACE-inhibition to maintain LZ+ MYPT1 expression and the normal sensitivity to cGMP mediated smooth muscle relaxation following an MI [22] is not secondary to a decrease in blood pressure, as LZ+ MYPT1 expression is not preserved with prazosin [22], nor an effect of bradykinin, but rather due to the ability of the ACE-inhibitor to decrease Ang II.

However, definitive proof for in vivo 5-LO inhibition is still missing and the observed reduction in leukotriene levels in our rat model could also be secondary to a decrease in inflammatory cell influx mediated by other unrelated mechanisms.

This RBC "storage lesion" also alters oxygen delivery (because of the higher affinity of hemoglobin to oxygen secondary to a decrease in 2,3-DPG) and pH and, in addition, it increases cell lysis[10].

This reduction in IKur is secondary to a decrease in the expression of Kv1.5.

Data suggest that the pain-reducing effects of glucocorticoids can be secondary to a decrease in local edema [ 17].