Sentence examples for a second occurrence of from inspiring English sources

If a second occurrence of >grade 1 toxicity occurred, sunitinib was further reduced to 12.5 mg.

The drug was discontinued in case of a second occurrence of severe toxicity.

The patient discontinued volasertib after a second occurrence of DLT (grade 4 thrombocytopenia) at 300 mg.

For patients who experienced a second occurrence of grade 3 4 toxicity, a further reduction by 50% was permitted.

In patients experiencing a second occurrence of grade 2 neurosensory toxicity, treatment was interrupted, and the oxaliplatin dose reduced to 85 mg m−2.

Capecitabine dose was reduced by 25% for patients who experienced a second occurrence of a given grade 2 event or any grade 3 event.

At a third occurrence of >grade 1 toxicity, sunitinib was discontinued.

Afatinib was discontinued after a third occurrence of AEs as specified above.

A Cox model was used to identify the correlates of a first occurrence of a major CADE.

Treatment in these patients was discontinued in the event of a fourth occurrence of a grade 3 reaction.

The fossil record suggests a first occurrence of the black bear lineage at least 1.8 Ma Kurténn and Anderson 1980).