Sentence examples for a second major difficulty from inspiring English sources

A second major difficulty was the world I was flung into.

A second major difficulty in developing the republican idea of freedom lies in giving precise meaning to the notion of arbitrariness.

Continuity theorists such as Pierre Duhem (1906), John Herman Randall (1940), A. C. Crombie (1959, 1994), and more recent historians such as Peter Dear (2001) have pointed out a second major difficulty in speaking of "the Scientific Revolution".

The second major difficulty stemmed from the time reversibility of the kinetic theory.

The second major difficulty is along the same lines, concerning, not functions, but relations, and thus ordering relations and ordinal numbers.

The second major difficulty arose in generation 12 of the TM strain.

The second major difficulty is the lack of efficient methods to integrate multiple levels of biological data to enhance model accuracy.

The third major difficulty South London Healthcare has faced is that it is saddled with paying off two private finance schemes, which were used to build the hospitals in Orpington and Woolwich.

A second major reason for alignment difficulties is the diversity of methylation patterns at cytosine loci.

A second major challenge of mass balances is the difficulty of detecting and quantifying target analytes in difficult matrixes including raw sewage and, more importantly, municipal sludge.

Obama administration officials knew about most of these difficulties before the Energy Department agreed in September 2010 to partly guarantee a second major loan to Nevada Geothermal, worth $98.5 million.