(A ) A cartoon of the AR mutagenesis screen developed to identify enzalutamide resistance mutations.
In agreement, we have also recently identified several subunits of this complex in a transcriptional screening developed to identify mutants defective in the induction of MLP1, a transcriptional reporter of the CWI pathway [ 53].
The five-item Brief Symptom Rating Scale (BSRS-5) is a screening instrument developed to screen psychiatric illnesses in non-psychiatric health settings [ 9].
A screen was developed to target this pool under hypoxic conditions eventually thereby identifying compounds with activity against non-replicating Mtb (Mak et al, 2012).
A screen was developed to measure the differential activity of small molecules on the growth and survival of patient-derived normal breast and metastatic, chemoresistant tumor cells to identify selective anti-cancer compounds.
A genetic screen was developed to identify suppressor mutations that could restore catalytic activity from a kinase-dead mutant of PKA.
A genetic screen was developed to identify suppressor mutations that restored catalytic activity in vivo from two kinase-dead Protein Kinase A mutants in S. cerevisiae.
In a search for chemical compounds that could restore normal cholesterol distribution in NPC mutant cells, an automated microscopy screen was developed to identify compounds that partially correct cholesterol accumulation in Chinese hamster ovary (CHO) NPC1-deficient cultured cells [39].
Interestingly, a novel computational-based screen was developed to identify lead compounds targeting the ubiquitin-mediated proteasomal degradation of frataxin (Rufini et al., 2011).
The first time my father looked at me was on a screen, using technology developed to detect flaws in the hulls of ships.
