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The nsSNPs extracted from public SNP databases were previously reported [ 20, 21], however, only the nsSNPs that were found in ≥2 chromosomes in a sample panel of ≥46 chromosomes were included into that manuscript.
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A single ddPCR is comprised of approximately 20 000 partitioned droplets, a number which is about 25 times the 765 chambers of a single sample panel on a microfluidic cdPCR array.
Levels of gene expression were normalized using GENORM software (25), which determines the most stable reference (housekeeping) genes from a set of tested candidate reference genes in a given sample panel.
The expression profile of selected chromatin remodelling genes from the three classes of histone modifiers was analysed in a large sample panel.
The MS-HRM technology allowed us to perform methylation screening with the capability of evaluating heterogeneous methylation in a large sample panel [ 9].
Figure 3 LC-MS/MS chromatograms for a typical blank rat plasma sample (panel A), the same blank plasma sample spiked with yakuchinone B (IS, panel B), a mixture of standard yakuchinone A and IS (panel C), and an IS-spiked plasma sample obtained from a rat 5 min after receiving a single oral dose of Suoquan capsules at 5.7 g/kg (panel D).
We estimate three versions of equation (1) for the full sample (Panel A) and separately for residents of the three transition states (Panel B).
Table 3 again splits the regressions into those relating to the full sample (Panel A) and the large city sample (Panel B), and employs all relevant control characteristics, including the selection correction and income inequality measures (as well as year and region dummies)5.
The geNorm software uses pairwise comparison method to calculate gene expression stability measure "M" for a potential reference gene in a given cDNA sample panel.
Therefore, standardization of methods for the quantification of 25(OH D on a human-based sample panel would be required to reduce the inter-method variability and establish reference values for 25(OH D in further studies.
Genet., submitted) has examined 69 risk regions among a multi-ethnic sample panel comprising European (8600 cases and 6946 controls), African (5327 cases and 5136 controls), Asian (2563 cases and 4391 controls) and Latino (1034 cases and 1046 controls) ethnicities.
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