The trial commenced in April 2006, and patient recruitment was completed in May 2009, resulting in a sample of 251 randomized patients.
Our study had 2 objectives: 1) To determine the magnitude of treatment effects in a sample of orthopaedic randomized trials with statistically significant results and 2) to examine the association between the number of outcome events (a measure of study sample size) and the size of the treatment effect.
A Data Collection Form (DCF) and a Procedure Manual including a Clinical Protocol based on an updated Practice Guideline will be designed [ 30]. 2. A pilot study has already been conducted on a sample of 20 randomized patients in five health centers located in Barcelona and Córdoba, where five GP and five nurses participated.
In order to examine the relationships between funding source, trial outcome and reporting quality, recent issues of five peer-reviewed, high impact factor, general medical journals were hand-searched to identify a sample of 100 randomized controlled trials (20 trials/journal).
10 11 In this analysis we evaluated a sample (n=200) of randomized controlled trials published in high impact journals in 2009.
We selected a sample of reports of non-randomized studies evaluating an intervention published in 25 journals of the BioMed Central Medical Series that regularly publish clinical studies.
The purpose of this study was to assess the accuracy and precision of self-reported research weights and heights in a sample of women enrolled in a randomized controlled trial, the Avoiding Diabetes After Pregnancy Trial (ADAPT).
To regularly check this, the Data Safety Monitoring Board (DSMB) will evaluate the global frequency of reproductive adverse events or pregnancy complications in the total sample of randomized women, and will communicate it to the General Coordination Centre GCCC).
Six of the included studies (five randomized and one non-randomized), representing a sample of 1328 treated patients, reported on cost effects [ 26, 28, 31, 33, 34, 39].
