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We can identify the conditions that make hardening likely from a simple comparison of timescales: Hardening should occur whenever Θ ≥ 1 and at the same time Δ T < τ ′ e s t, (3)such that a second de novo mutation typically does not have enough time to reach a safe frequency that assures its survival before the next bottleneck sets in.
The argument that the second adaptive mutation needs to grow for τ2 generations after its establishment to reach a safe frequency 1/ N2 makes sense only when the mutation is actually at a lower frequency than 1/ N2 at establishment, which requires that bottlenecks are sufficiently severe (N2/ N1 < s).
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Finally we introduce our AutoTEA system, which automatically adds circuitry to arbitrary FPGA designs for dynamically adjusting clock-frequency to a safe limit given current operating conditions.
Even in the conventional field of application of nickel-base alloys (e.g. turbine blades) superimposed high frequency loading requires a safe life at very high number of cycles.
The aim of this study was to explore if positive-pressure ventilation delivered by a conventional ICU ventilator at a moderately high frequency (HFPPV) allows a safe reduction of tidal volume (VT) below 6 mL/kg in a porcine model of severe acute respiratory distress syndrome (ARDS) and at a lower mean airway pressure than high-frequency oscillatory ventilation (HFOV).
Sterilization phases were programmed to recur at the highest frequency compatible with a safe propagation of the culture, i.e. one nutrient flow reversal and one sterilization phase per 48 h for a 2-h generation time.
13 High frequency ultrasonography is a safe, accurate, readily available technique for guiding musculoskeletal aspiration and infiltration that ensures correct placement of the needle and delivery of the drug.
High-frequency ultrasound is a safe, cost-effective, and widely available modality for the evaluation of facial fillers.
Then the range of natural frequencies is provided for a safe design purpose.
Simulation can offer a safe training environment to practice high-risk/low-frequency medical scenarios and engage learners on multiple levels: cognitive, procedural, and affective [ 4].
For example, a processor may reduce the core operation frequency when the temperature rises above a safe threshold or to maintain the system within the power budget target.
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