The goal of this study was to detect the possible safe concentration of MNPs (average diameter = 10 nm) on the cells.
There is no safe concentration of radon gas, but guideline values provide threshold concentrations that are used to map areas at higher risk.
The clinical and public health relevance of the findings are not easily established, but our results suggest that the safe concentration of uranium in drinking water may be within the range of the proposed guideline values of 2-30 microg/L.
The maximum safe concentration of 1 was 250 μg/mL tested by preliminary experiment with MTT method while that of 2 was 1250 μg/mL. 1 was serially twofold diluted with MM from 250 μg/mL to 31.25 μg/mL, and 2 from 1250 μg/mL to 156.25 μg/mL, thus obtaining 4 concentrations each.
A trial aimed at establishing safe concentrations of pyruvate for human use was recently completed at UCSF.
Our results demonstrate that the choice of the experimental conditions and the toxicity testing protocols plays a relevant role in determining the safe concentrations of potential hazards of nanomaterials.
Vaporizers are an integral part of modern-day anaesthesia, allowing the delivery of safe concentrations of volatile anaesthetic agent.
This will identify tube wells with safe concentrations of As, Mn, and U for additional evaluation as a potential drinking water supply in these neighborhoods without the cost or delay of testing for all nine elements.
