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In young-onset diabetes, insulin therapy status is a rough marker of diabetes type.
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Admittedly, race is a rough marker.
In three Italian university ICUs we measured plasma ADMA, SDMA, their ratio (a marker of ADMA catabolism, a rough indicator of DDAH activity), arginine, IL-6, TNFα, and C-reactive protein (CRP) level at days 1, 3, 6, 9, 12 and at discharge in 72 consecutive patients with severe sepsis/septic shock.
In particular, dS will serve as a neutral divergence marker among vertebrates while dN will provide a rough indicator of sequence alignment quality across larger phylogenetic distances.
Dividing the recombination frequency between flanking markers calculated in step 4a by the physical distance between those markers in the maize genome will provide a rough estimate of recombination rate around your mutation.
As we had three repeats of the same history, we inferred a rough estimate of the age of the cline using the difference in behavior among microsatellite markers.
"Colonists had a rough go of it.
Your fourth hitter has had a rough time of it.
Nostalgic tennis types have had a rough go of late.
They had a rough go of it.
"It was a rough couple of years".
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