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Taking these findings together with those from XPS (including ARXPS and VBS), in situ XAS, and HRTEM-EELS, we propose that the Cu+ support may play a role in selectivity toward C2+.
These mutations were created on a C479T background, since Thr at this position in K+ channels plays a role in selectivity [20], [32] by forming the 4th ion binding site [15], [16].
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The results suggest that packing plays a role in shape selectivity similar to that demonstrated previously for size selectivity.
The compartmentalization of caspases, the duration of the caspase signal, or the coordinated expression of antiapoptotic molecules might play a role in the selectivity of caspase cleavage.
Furthermore, the concentration of the surface OH groups was found to play a role in the selectivity for the formation of CH3OH.
Furthermore, the smooth surface of the CNTs may also play a role in the selectivity derivation of gas molecules from the Knudsen diffusion.
This suggests that the carboxylic tail may play a role in functional selectivity in 5-HT4 or 5-HT2C receptors (Figure S3).
The subcellular localization could also play a role in substrate selectivity and detailed knowledge on the processing would be helpful in designing therapeutic compounds that specifically inhibits Aβ production.
Additionally, regions beyond the RBDs of RGS14, e.g., the RGS domain and GoLoco motif, may play a role in the selectivity of RGS14 for activated H-Ras in cells.
They are likely to hold the key to specificity in terms of targeting these proteases to protein complexes and cellular compartments, serve regulatory functions, and play a role in substrate selectivity such as in the most well studied member of the USP family USP7/HAUSP.
Our observations are consistent with the previous demonstration that mutation of one or a few residues in the NHR RH can result in dramatic changes in sequence preferences, but that mutations elsewhere in the DBD play a role in sequence selectivity (e.g., McKeown et al., 2014).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com