The phrase "a role in activation" is correct and usable in written English.
It can be used in contexts discussing functions or contributions to a process, particularly in scientific or technical discussions.
Example: "The protein has a crucial role in activation of the immune response."
Alternatives: "a part in activation" or "a function in activation".
KSR1, originally described as a novel protein kinase, has a role in activation of mitogen-activated protein kinases.
Phosphatase activity of calcineurin plays a role in activation of T cells [ 196].
MMP-3 also has a role in activation of proMMP-1 in tumor tissue into the active form of MMP-1 [ 4].
Although the relationship between Wnt proteins and VEGF during skeletal development has not yet been clarified, Wnt/β-catenin signaling has been suggested to play a role in activation of VEGF gene expression in benign colonic adenomas in which mutant activated Wnt/β-catenin pathway is often associated with up-regulated VEGF [49].
L-selectin plays a role in activation of naïve lymphocytes that participate in immune surveillance and antitumor immunity.
Compelling evidence indicated that the C-terminal domain might have a role in activation of the kinase [34] [36], and function in protein-protein interactions mainly involved in ABA responsiveness, and possibly involved in ABA signal transmission [22].
These data indicate that although other possible mediators exist, one possible downstream target of miR-21 that has a role in activation-induced T-cell apoptosis is Tipe2.
24 The decreased expression of the pro-apoptotic molecule BNIP3L in SLE patients is particularly interesting as it is a functional homologue of BNIP3, which has been shown to play a role in activation-induced T-cell death.
IL-32 (primarily IL-32β) expression in activated CD4 + T cells was also associated with increased apoptosis and was presumed to play a role in activation-induced cell death [ 23].
CDKD1 3 plays a role in the activation of CDK activity during cell cycle reentry [ 26].
In addition to a role in the activation of NFκB signaling, SopE seems to also have a role in the activation of Caspase-1.
