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It may be that different combinations of genes can lead to an antigenically or structurally similar final capsule that confers the phenotype, but this can only be hypothesised when a robust study on the relationship between capsule genetics and final produced capsule is performed.
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These hypothesis lay on a robust study recently published by Ellis group, where although a trend (non-significant) to display lymph node involvement with increasing tumour size was seen (especially in tumours larger than 4 cm), basal-like tumours do not seem to obey the "size-node" rule [ 56].
Nevertheless these do not remove the essence of the study objective but will serve as the basis for further robust study on the subject.
Therefore, from a therapeutic point of view, more robust studies on the function of GAS6 in ovarian cancer are required.
Many health promotion and prevention measures, by contrast, (also) address the societal level and the environment, but there are few robust studies on their effectiveness, not least because of a lack of resources, the complexity of the measures, or randomisation problems.
But we won't fully understand how much effort open offices need to sink into maintaining health for their employees relative to offices with private, enclosed spaces until we conduct more robust studies on how much each potential risk factor in an open layout can impact workers' wellbeing.
Furthermore, very few robust studies on this subject are generalisable to situations in the real world.
However, robust studies on the influence of sex on the association between serum ferritin and diabetes are rather inconsistent.
Therefore, the development of successful control programs requires robust studies on the reproductive traits (such as male mating ability, reproductive success and sperm transfer) of irradiated males compared to non-irradiated males.
Robust study design based on mixed methods.
Robust study design based on multicentre nationwide randomised control trial.
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