Because many factors such as RNA isolation, labeling and hybridization methods affect the quality of microarray data, pooling data from different experiments does not allow for a rigorous expression profiling analysis.
We make a rigorous exploration of the profiles of off-diagonal components of frequency-dependent linear (αxy, αyx), first nonlinear (βxyy, βyxx), and second nonlinear (γxxyy, γyyxx) polarizabilities of quantum dots driven by Gaussian white noise.
To enable a rigorous comparison of different replication profiles and, in particular, to define more rigorously the unique profile of mrc1 deleted cells, we revisited the data we reported previously describing the replication profiles of mutants with an extended S phase [ 19].
The present work is a rigorous analysis of the general profile of experimental colitis induced by DSS, including the clinical, histological characteristics, as well as inflammatory indicators and mediators in a spatial and temporal fashion.
We utilized the advancements presented in these studies (shearing of genomic DNA to minimize size-based bias during amplification and use of the Illumina sequencing platform to obtain in-depth tumor profiles) to conduct a rigorous assessment of the relationship between template abundance and sequencing depth.
To test the PHOG-BLAST procedure, we compared it with PSI-BLAST [ 7], a well-known algorithm for fast profile search, and with COMPASS [ 18], one of the best rigorous profile-profile comparison methods.
In conclusion, we present a rigorous analysis of DSS-induced colitis, a commonly used animal model of IBD, correlating cytokine profile with clinical and histological parameters as well as barrier properties.
A rigorous screening of the stool and its donor is mandatory from clinical data to metagenomic analysis (including taxonomic and gene-centric profiling).
Again, a rigorous test of all hypotheses is critical.
Military officials describe a rigorous process of picking targets.
