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From very general considerations, a rigid differentiation program and complex shape of the neuron makes it an inherently disadvantaged cell type.
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A headache attack with migraine phenotype in patients with epilepsy thus might be associated with otherwise clinically silent seizures, calling into question the rigid differentiation between interictal and ictal headache.
This observed plasticity of normal tissue stem cells has implications for tissue organization in general, and the view of rigid differentiation hierarchies of cells must be revised in light of these findings.
In contrast, a rigid matrix facilitates CM differentiation, characterized by tightly packed arrays of long and aligned sarcomeric bundles, cell cycle arrest, and binucleation.
To further investigate whether switching from a rigid to a compliant matrix environment promoted differentiation at the cellular level, we performed confocal immunofluorescence.
A decade ago, fashion was a rigid system.
They undergo a specific differentiation process and form the cornified envelope, which is a rigid and insoluble protein and lipid structure with essential properties of the barrier function [1], [2].
A key to arthropod success has been the differentiation of many serially repeated parts, in particular jointed appendages with a rigid exoskeleton, to perform the varied functions necessary to maintain life.
A lacrosse stick is a rigid slingshot.
Her back remains a rigid blockade.
Posture is not a rigid concept.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com