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A review protocol was drafted and registered on PROSPERO with number CRD42015026979.
We developed a review protocol, including a conceptual discussion of the research problem and a statement of its significance.
In the first phase, a review protocol is defined, in which research questions are specified along with search strategies.
This systematic review was executed directly based on the ascertained RCTs available and has not been registered as a review protocol.
Review planning: In this stage, the researcher creates a review protocol containing the research question, search terms, paper selection criteria, and the data extraction strategy.
According to Kitchenham (2004), there are three main stages in the execution of an SLR: Review planning: In this stage, the researcher creates a review protocol containing the research question, search terms, paper selection criteria, and the data extraction strategy.
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A systematic review adopts a rigorous procedure by defining a formal review protocol.
We developed a comprehensive review protocol and implemented an electronic search strategy to identify relevant citations in Medline, EMBASE, DARE and Cochrane.
The work was conducted as part of a Cochrane Review and followed a prospective review protocol [27].
Data from all children were reviewed daily and there were a priori defined stopping rules which would trigger a suspension of the trial and a safety review (Protocol S1).
Briefly, we established an expert working group to develop a structured review protocol and execute the search and synthesis of reports of relevant studies.
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