Exact(1)
Data were provided showing that a ceramidase activity inherent to the AdipoRs was fundamental to adiponectin's effects, through a reduction in ceramide and an increase in antiapoptotic sphingosine-1 phosphate (S1P) levels, and hypothesized that a resulting release of calcium from the endoplasmic reticulum might activate AMPK downstream via CAMKKβ.
Similar(59)
Previous investigations have focussed on defective placental implantation as an important aetiological factor, with the resulting release of placentally derived circulating factors, which cause endothelial dysfunction [ 2– 4].
As a result, release of a number of pro-inflammatory cytokines (e.g. MCP-1, IL-6) by adipocytes is suppressed (Ajuwon and Spurlock, 2005; Dietze-Schroeder et al., 2005).
More recently, the muddying of Lower Esopus Creek, a popular waterway in Ulster County, as a result of releases of turbid water from the city's reservoirs has led local officials to compare the city to "an occupying nation".
As a result, the release of Fe3+ from holo-Tf is facilitated (Zhao et al., 2010).
An important conclusion is consequently reached that deep cracks occurred as a result of release of high ground stress including gravitational stress and tectonic stress.
Initially, there is an increase in blood supply to this region [ 28], probably as a result of release of local vasodilators [ 29].
Endothelium plays a central role in the physiological maintenance of vascular function by regulating vascular tone, leukocyte adhesion and platelet activation, as a result of release of vasoactive substances such as nitric oxide (NO), prostacyclin and endothelin [ 3].
We see this clinical phenotype as a result of release of fatty acids by peripheral adipocytes, which in turn is due to a decrease in mitochondrial capacity to remove fatty acids.
As a result, lipolytic release of free fatty acids is enhanced in large adipocytes, leading to cytotoxic fatty acid accumulation in extra-adipose tissue (Unger, 2003).
There could be particulate release as a result of loss of containment or fire".
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