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The updated version of this model posits that psychopathy is a result of a dysfunction of the amygdala, the almond-shaped bundle of gray matter situated in the midbrain, which is another area instrumental in emotional processing.
The malignant transformation of thyroid C cells is associated with an increased production of human calcitonin as a result of a dysfunction of the regulatory system.
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The association between depression, anxiety, and headaches/migraines is proposed to be a result of a neurolimbic dysfunction [ 32], where shared pathways in the limbic system are altered.
The nature of the age-related risk remains largely unknown, and whether it arises from cell autonomous mechanisms or as a result of a systemic dysfunction remains to be determined.
But Ross et al. reason as follows: the existing category "maps relatively smoothly onto the class of people who exhibit classic patterns of addictive behaviour as a result of a specific kind of dysfunction in their dopaminergic reward system and consequent neuroadaptation impairing frontal control circuits.
Patients with long-term ACEI therapy have higher risk of postoperative renal dysfunction as a result of a loss of ability of the renin angiotensin system to compensate for decreases in renal perfusion [86, 87].
In conclusion, we believe this to be the first in vivo observation to document the early development of CVD (endothelial dysfunction) as a result of a single protein mutation involved in NF-ĸB signaling, relevant to previously reported clinical genome-wide association studies for SLE.
There has been an improved understanding of organ dysfunction, mainly as a result of a close collaboration between hematologists/oncologists and intensivists [24] (Table 2).
The following year, melamine contamination of infant formula in China led to the hospitalization of more than 50,000 infants as a result of renal dysfunction.
Reduced cellular adhesiveness as a result of cadherin dysfunction is a defining feature of cancer.
Oxidative stress generated as a result of mitochondrial dysfunction has been implicated as an important factor in the etiology of Parkinson's disease.
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