Therefore, a very restricted release of cytokines in time and space could be desired for most of their therapeutic applications.
The restricted release of neutrophil-derived proteins in dexamethasone treated patients may have contributed to the significant reduction in CSF protein observed in the dexamethasone group in the published study involving a larger number of patients from the parent trial [2].
Taken together, the combined results of our microarray and quantitative RT-PCR analyses provides strong evidence that the infection of monocyte-derived macrophages with S. aureus upregulates the transcription of antiapoptotic genes, which likely explains the observed restricted release of cytochrome c from mitochondria upon STS treatment.
However, current amplitudes of unitary interneuron-NG2 cell connections are very small compared to extracellularly evoked currents, suggesting that a single NG2 cell is densely connected by many interneurons in the network, but that a single interneuron contacts a glial progenitor through a restricted number of release sites.
Despite being part of a wave of offbeat films that mostly failed to make an impact at the box office, it drew public attention upon its release, which led to a commercial success among a restricted audience targeted by a selective release in twenty cities.
After years of legal battling, a small part of a vast archive of files compiled by the former East German secret police, the Stasi, on former Chancellor Helmut Kohl was released to a restricted group of researchers and journalists.
Two years later, Starling coined the term hormone to denote such substances released in a restricted part of the body (endocrine gland), carried by the bloodstream to unconnected parts, where, in extremely small quantities, they are capable of profoundly influencing the function of those parts.
Upon his release, he was designated a "restricted person" and sent back to his home district, Luwingu, in a rural part of the country.
Also, it may only be loaded with a restricted range of antibiotics and the long-lasting release may induce antibiotic resistance [ 27, 33, 38].
Mystery Train was released theatrically by Orion Classics under a restricted rating in the United States, where it grossed over $1.5 million.
