Sentence examples for a restricted pattern of from inspiring English sources

In contrast, aged R1441C LRRK2 transgenic mice with a restricted pattern of transgene expression display reduced levels of cortical catecholamines, a progressive impairment of locomotor activity and the accumulation of autophagic vacuoles in the cerebral cortex.

Conversely, genes, mutations in which lead to cardiomyopathy, are very highly correlated with each other (p = 6.4×10−146) indicating that a restricted pattern of expression is common for this group of disease genes.

To address this, we first performed luciferase assays on sorted mammary epithelial cells from the luciferase transgenic mice just after giving birth to pups (near the peak in both number and percentage of MaSCs) and observed a restricted pattern of luciferase expression in CD24+CD29hi MaSCs similar to virgin controls (Fig. S2).

The majority of the E-cadherin positive cases (8 out of 9 cases) exhibited a restricted pattern of E-cadherin immunostaining, in which E-cadherin was focally expressed in discrete nests of tumor cells, usually reflecting areas of epithelial-like differentiation (Figure 1A, Ai).

These proteins have a restricted pattern of expression and typically contain only one HMG-box [ 10].

ARSE exhibits a restricted pattern of expression [ 23] while ARSD is ubiquitously expressed [ 36].

In this paper we describe a GT insertion which displays a very restricted pattern of expression in the gastrulating embryo.

Without a more restricted pattern of gene expression, the deleterious effects of these neomorphic c-Myb and A-Myb proteins would almost certainly have led to extinction without rapid pseudogenization and/or gene loss.

While GNAQ and GNA11 are ubiquitously expressed, other members of the family show a very restricted pattern of expression.

In contrast to MLK3, which is widely expressed in many tissues [21], the MLK family member dual leucine zipper-bearing kinase (DLK) exhibits a more restricted pattern of expression [22], [23].

Yet the low number of DRP-1β ESTs stands in contrast to the numerous ESTs of DAPk, DRP-1 and ZIPk reported to date (Table S1), suggesting that unlike the ubiquitous expression of the three well known family members the new alternate isoform may have a more restricted pattern of expression.