Exact(8)
IL-29 has been shown to activate monocytes and macrophages to produce a restricted panel of cytokines.
Systemic lupus erythematosus is a severe systemic autoimmune disease characterized by loss of tolerance towards a restricted panel of autoantigens.
However, such a comparison is intrinsically limited, since these SNPs were ascertained in a restricted panel of domestic dogs.
A restricted panel of ALT and ALP was an efficient choice of analytes, comparing favourably with the complete panel of eight analytes, provided that 48 False Positives can be tolerated to obtain one additional True Positive.
A restricted panel assay exhibited a sensitivity of 48%9595% CI: 42 54%) with a specificity of 96%9595% CI: 91 99%) in the validation cohort (Table 2 and 3).
This older technology may be suitable for genotyping a restricted panel of selected loci, but amplification from the ends of genomic fragments is definitely more restrictive than random priming.
Similar(51)
Interestingly, the over-expression only implicates IR with a broad spectrum of HLA class I ligands, but no receptors of the KIR family [24] that have a more restricted panel of ligands.
Although a five-marker panel has been identified to categorise breast cancer (Cheang et al, 2008), the biological determinants underlying the different clinical behaviour between the molecular subtypes is clearly more complex than implied by such a restricted biomarker panel.
Taking into account the cost benefit, autoantibody assays against the restricted panel is acceptable for aiding the early detection of ESCC.
The restricted panel consisting of the four antigens p53, NY-ESO-1, Hsp70, and Prx VI exhibited almost the same diagnostic performance as when screening for all six autoantibodies.
Therefore, the drawback of potentially missing associated non-inflammation genes is offset by the increased probability of detecting true associations in an inflammation-restricted panel.
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