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Then, the α-Gal A responses from HEK-293 cells were compared to the patient PBMC α-Gal A responses from the Phase 2 studies (Table 2).
(A ) Responses from a S → A rod to a dim, full-field flash, delivering 1.2 photons/μm, classified as either a response (gray) or failure (black).
(A ) Responses from WT, T → A, and Combo lines were binned according to their duration, in 1-s wide bins every 0.5 s (oversampling) and aligned to their termination points (gray lines).
DOI: http://dx.doi.org/10.7554/eLife.05981.014 10.7554/eLiFigure8 figureigure 8—figure supplement 1. Termination-aligned S → A responses exhibit recovery time constants of ∼200 ms. (A ) Responses from WT and S → A lines were binned according to their duration, in 1-s wide bins every 0.5 s (oversampling) and aligned to their termination points (gray lines).
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