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When thrombocytopenia (platelet count <25 × 10/l) is diagnosed at presentation, based on the rationale that once a response is achieved thrombocytopenia is likely to resolve, some experts would consider administering lenalidomide with platelet support (Table 5 and Fig. 1).
Although the optimum time period for hormonal treatment has not been extensively explored, some studies suggest that the maximum response is obtained during the first 3 4 months of treatment, whereas other investigators state that >9 months can elapse before a response is achieved (Allan et al, 1985; Gil et al, 2001; Krainick-Strobel et al, 2008).
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68 Patients were treated for a median of 4 cycles, with only 2 additional cycles administered as consolidation if a response was achieved after 4 cycles.
If only a partial response is achieved a TCA should be tried (or a non-TCA antidepressant if a TCA was used in Stage 1).
Avoidance learning is a classical conditioning paradigm in which a conditioned response is achieved after multiple pairings of neutral conditioned stimuli (CS) and aversive unconditioned stimuli (US).
Therefore, the filter polynomials are adjusted such that a required bandwidth with an equiripple response is achieved.
A more stable response is achieved with this type of modern control.
A constitutive ethylene triple response is achieved by expressing putative C-terminal EIN2-cleaved fragments [ 45].
In this case, acetaminophen is used and, if no response is achieved, a nonselective NSAID is prescribed.
The specificity of this response is achieved by a surveillance system that detects aberrant RNA.
A complete response was achieved in 109 patients, and a partial response in 25 patients.
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