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As an example, we demonstrate here that ART can overcome apoptosis resistance of Doxorubicin in a resistant cell line.
Cytotoxicity (WST-1 methods) and functional (calcein acetoxymethyl (Calcein AM)) assays were performed on a resistant cell line K-562/doxR and on the mononuclear cells (MNCs) of patients with AML.
The probability that a resistant cell is generated in turn depends on the growth kinetics of the cancer cell population, which are influenced by regulatory processes such as quiescence and cell death.
YAPC is a resistant cell line with a KRAS amplification and KRASV12 mutation.
The time required to select for a resistant cell population varied for the different cell lines.
G3139 effectively reduced Bcl-2 expression and enabled Fas-induced apoptosis in a resistant cell line with low levels of Fas expression.
Similar(48)
Zygospores generally have a large store of food reserves and a thick, resistant cell wall.
Bacteria in this genus can produce a highly resistant cell type, the spore, which is encased in a complex protective protein shell called the coat.
In addition, in vitro studies were performed in a drug resistant cell model using the 100-fold MTX resistant breast cancer cells MDA-MB-231.
Careful adjustment of amine basicity was essential for preserving cellular potency in a multidrug resistant cell line while maintaining good aqueous solubility.
The MCF-7DOXR cell line is a doxorubicin resistant cell line derived from parental MCF-7 cells.
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