CESAs are membrane-spanning proteins and small side chain residues often occur at the TMDs as a requirement of helix folding and structural stability.
In molecular imaging, the development of suitable radiolabeled probes requires a rational design based on the structure biological activity biodistribution relationship because the requirement of structural specificity for a radiolabeled probe is rigidity for binding to the respective DNA, mRNA, receptor, transporter and enzyme.
Further, the requirement of structural similarity, involving a reasonable conservation of bulge size and location in the hairpin stem region of the predicted miRNA precursors, could be decreased between these two species of Ciona.
These results present a compliance between the detrimental effect of surface inhomogeneities and the primary requirement of structural integrity during service life.
Moreover, according to Malone et al. [14], the rigid characteristics of the volar locking plates are strong enough to avoid the requirement of structural bone grafting.
The compressive strengths of OPS concrete range from 20 to 24 N/mm2 for 28 days; this satisfies the strength requirement of structural lightweight concrete.
The lower melting temperature of promoter regions could be due to the requirement of structural adaptation by DNA to facilitate specific binding of regulatory proteins, while the lower melting temperatures of introns relative to corresponding exons might be due to their low thermodynamic stability, as also observed independently by Wada and Suyama two and half decades ago [60].
The ability of a structural joint to maintain satisfactory long-term performance, often in severe environments, is an important requirement of a structural adhesive joint, as the joint should be able to support design loads, under service conditions, for the planned life time of the structure.
According to JCSS (2001), the reliability index target expresses the requirements of structural safety, which guarantees acceptable values of structural failure risk considering a given scenario.
Key concepts are first introduced in terms of general requirements of structural crashworthiness and occupant safety.
