Sentence examples for a required role from inspiring English sources

While we can not formally rule out the possibility that Tim depletion induces some level of S phase checkpoint activation that blocks or delays recombination structure formation, our findings are most consistent with a required role of Tim in generating recombination structures at replication fork barriers [18].

Further analysis revealed a required role for SHP-2 in mesenchyme of the progress zone in limb buds.

Caveolin-1 and cavin-1 play a required role in that their expression is necessary to stabilize cavin-3 levels.

At the molecular level, abnormalities reflect a required role for SHP-2 in the activation of ERK and AKT kinases in bone-forming cells.

The authors discuss the recent findings of Andy Larner and David Levy [ 16, 17] that establish the presence of non-tyrosine phosphorylated STAT3 in mitochondria that plays a required role in transformation by the Ras oncogene.

Because there was a strong association between MSC elongation and tenocytic differentiation, we posited that mechanisms that regulate cell morphogenesis (i.e., shape) play a required role in the differentiation process.

While RabX1 and RabX2 are restricted to the trypanosomatids, we find evidence for expression in T. brucei, T. cruzi and Leishmania, suggesting a conserved and required role amongst a broad range of protists.

Girls require role models and guidance.

They use the same lawyer for their FCC filings, they share the same offices, and Facebook recently advertised for an "Extra-Terrestrial Product Manager," a role requiring an "in-depth technical knowledge of satellite communication systems".

Getting people to buy local ingredients is a relatively simple matter of changing purchasing behavior; getting them to cook will require a role model who really seems to mean it.

But Mr. Marshall and others were dead set against having someone they regarded as a fluffy, pubescent pop star in a role that required a brutal edge.