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A YopE defective background was chosen for this assay in order to avoid a repressing effect on pore formation and thereby influence of ExoS translocation efficiency [74].
The mechanism that determines the context-dependent switch between a repressing versus activating mode of SHARP function remains to be determined.
Interestingly, the transcription factor DksA, which normally acts synergistically with ppGpp, showed a repressing effect on rsd expression, indicating the possibility of a differential regulation by DksA and ppGpp.
In general [3], [8], methylation on H3K4, H3K36, and H3K79 has an activating effect on gene expression [6], [9], whereas methylation of H3K9, H3K27, and H4K20 impose a repressing effect on transcription [10] [13].
A transcription factor may regulate gene expression in an enhancing or a repressing manner.
Strongest induction occurs by using low concentrations (0.5 mM), whereas high concentrations lead to a repressing effect on xylanase expression [ 7].
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R. Narc A repressed, volatile Detroit cop named Nick Tellis Jason Patricc) is assigned to find a cop killer.
In that word, "different," was a repressed shudder.
To the Editor: After reading "Singapore: A Repressed City-State?
Was it a subliminal expression of a repressed desire to be a powerful statesmen?
And it is such an emotional outlet, especially for a repressed society.
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