Your English writing platform
Discover LudwigExact(14)
For instance, the number of created proteins is a random variable due to thermal fluctuations in a cell which cause promotors to randomly switch between an active and a repressed state.
Moreover, the imposition of a repressed state by Swm1/2 involves one of the HDACs – Clr6.
This fraction may correspond to genes that can rapidly switch between an activated and a repressed state.
While acetylation of lysine (K) residues in general is associated with transcriptional activity, methylation of lysines can be associated with maintenance of an active or a repressed state depending on the position of the modified residues.
UC cell lines showed ratios between 1 2 and 1 5 indicating a repressed state.
In most cases, it appears that RNAi-based mechanisms are focused on the transgenerational inheritance of a repressed state.
Similar(46)
In contrast, a strong reduction in Ac-H3 level that cannot be offset by a weak Ac-H4 increase as observed at the HEXIM1 promoter could be an indicator of a permanently repressed state caused by i-CDK9.
Some of the mRNAs are maintained in a translationally repressed state and may be transported to a specific cytoplasmic location where translation is activated [ 46].
Together, these results suggest that human HSF1 expressed in yeast is maintained in a constitutively repressed state through mechanisms similar to those of mammalian cells and that the yeast system can serve as a simplified assay system to decipher the complex mechanisms regulating human HSF1 activity.
By accumulating H3K27me3 upon SC activation, the chromatin is converted to a more repressed state.
Instead, the mRNA appears to be maintained in a translationally repressed state independently (and despite) of the PTC.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com