Sentence examples for a representative compound of from inspiring English sources

RC307, a representative compound of this series, caused a growth-inhibitory effect in colon carcinoma cells HCT116 associated with G2 accumulation and induction of apoptosis.

Notably, the structure of NP in complex with a representative compound of these inhibitors revealed that two inhibitors in an antiparallel orientation lock two adjacent NP protomers.

Once the standardization of number of larvae was performed, the staining methodologies were further tested with a representative compound of each main class of available drugs currently used.

The Ni metallic phase supported metal oxides such as α-Al2O3, Ce0.75Zr0.25O2, and MgO were tested under the steam reforming of acetic acid selected as a representative compound for the aqueous phase of the bio-oil derived from biomass pyrolysis.

A representative compound blocked the progression of nonalcoholic steatohepatitis (NASH) in an animal model.

An X-ray crystal structure of a representative compound, AAL993 (ZK260253), in complex with the catalytic domain of diphosphorylated VEGF-R2 has revealed that this molecule binds to an inactive conformation of the protein.

The (S -enantiomer of a repreS -enantiomerpofnd exhibited extremely potent PParepresentativetion acompound comparablexhibited somextremelyerior to that of the known potentselective agonist, GW-501516.

Chemical modification of the core scaffold led to a representative compound 50, which showed strong inhibition of IAP binding (X chromosome-linked IAP [XIAP]: IC50 23 nM and cellular IAP [cIAP]: IC50 1.1 nM) and cell growth inhibition (MDA-MB-231 cells: GI50 2.8 nM) with high permeability and low potential of MDR1 substrate.

We also report the ex vivo NET occupancy of a representative compound, 41.

The single crystal X-ray data of a representative compound is presented.

We also demonstrate the anti-HIV activity of a representative compound 12, as measured in a p24 assay.