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This observation supports a reported architecture of the active site, with 3′-bridging and pro-SP non-bridging oxygen atoms of the scissile phosphate group involved in direct contact with hydrated magnesium cation, while His-89 activates a water molecule which attacks the phosphorus atom according to a one-step in-line mechanism.
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The performances of the reported architecture were assessed in terms of classification of stress conditions.
To compare with the reported architecture presented in [4] and [11, 12], the proposed architecture was also tested on Stratix EP1S25B672C7 FPGA.
The previously reported architecture of mtZFN monomers (Fig 1A) (Minczuk et al, 2008; Minczuk, 2010) was adapted by placing MTS-epitope tag-NES at the N-terminus.
The performance of the proposed optimized model is benchmarked with one of the previously reported architectures for a similar system.
A novel realization architecture is proposed that has higher performance and uses lower hardware resources in comparison to the other reported architectures.
The experimental result and performance comparison show better throughput of the proposed implementations as compared to existing reported architectures.
Comparisons are made between the multi-layer multi-granularity switching (MM-XC) architecture and the reported architectures: multi-switching (M-XC) and single switching (S-XC) architectures.
The proposed architecture gives high performance without any pipelining or parallelism in ACS and shows at least 13% throughput and 5× power improvement over the reported architectures.
While other technical specifications for data submission have not yet been published, CAT Reporters should start looking at their regulatory reporting architecture and identifying opportunities for consolidation and simplification.
The new concept XSLR analyses the opportunity of operating semantically with science-type taxonomies, defined according to the model of financial reporting architecture.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com