The phrase "a replication vector" is correct and usable in written English.
It can be used in scientific or technical contexts, particularly in molecular biology or genetics, to refer to a DNA molecule used to replicate a gene of interest.
Example: "Researchers utilized a replication vector to clone the desired gene for further study."
Alternatives: "a cloning vector" or "a DNA vector".
High permissivity of Rousettus cell lines could justify testing bats for susceptibility to MVA as a replication competent vector with low zoonotic potential to induce herd immunity in bat colonies against viruses causing rabies or haemorrhagic fevers.
Defective adenovirus vectors from species B adenoviruses have been reported[21][22][23], but a replication-competent vector to improve virus replication, cell lysis, and virus release has not been identified.
C4-2 cellshoweded maximal growth inhibition when coinfected with Ad-Flk1-Fc and Ad-hOC-E1, a conditional replication-competent Ad vector with viral replication driven by a human osteocalcin (hOC) promoter targeting both prostate cancer epithelial and stromal cells.
The localization of activated CD8+ T cells to the mesenteric nodes after several days in the immune response to a replication-defective vector challenge in the hind limb is unlikely to be due to migration of either antigen or antigen-presenting cells to these nodes.
Grill et al demonstrated that transduction of primary glioma spheroids with a replication-deficient vector resulted in the expression of the transgene in the outer rim of the spheroid only.
In a phase I/II trial Mincheff et al. found that all patients immunised with a replication deficient adenoviral vector expressing PSMA and later boosted with plasmid PSMA showed signs of immunisation (by DTH), while only 50%% of patients vaccinated with plasmid PSMA/CD86 alone showed signs of immunisation [100].
We assessed the ability of a replication deficient Ad5 vector encoding green fluorescent protein (GFP) to infect neurons following stereotaxic injection into the SNc.
Forced IL-24 expression driven by a replication incompetent adenoviral vector (ad.mda-7) has been demonstrated to selectively induce growth suppression and apoptosis in a broad spectrum of malignant cell lines in vitro while leaving normal cells unaffected [5], [6], [7], [8].
A replication defective adenoviral vector constitutively expressing human opticin was generated.
Kojima et al (1998a, b) described the construction of a replication deficient adenoviral vector containing the human liver CE1 gene driven by the CMV promoter.
