Horii introduced them as he wanted to have something players collected that were similar to the crests and orbs in the previous Dragon Quest games, but did not want to repeat the necessity for players having to collect a certain number of them before they could complete the game.
Against all reason, Byron's televangelist-led quest for clarity compels us to follow, the film's melting, naturalistic images softening the occasional scream of dialogue repeated beyond all necessity.
Recurrent infections are of particular concern because of the repeated morbidity and necessity for frequent administration of antibiotics with the possible adverse consequences of selection of antimicrobial-resistant strains.
If these limitations present, they should be addressed in the report, and a decision should be made on the necessity of repeated imaging or acquiring the data with alternative imaging modalities.
A fast automated analysis allows samples to be thawed and analyzed for several hormones within a single day, which, in the case of studies involving quantification of a battery of analytes from various hormone groups, will reduce the necessity for repeated thawing of samples and/or preparation of multiple small volume aliquots, which might increase losses and affect sample quality.
In case of necessity of repeated dilatations for biliary stenoses and lack of endoscopic access instead of leaving an external access catheter a transjejunal approach may be performed.
This is especially important in view of the off-label use and the necessity for repeated injections in most eyes.
This case also should bring to mind the necessity of repeated counselling about contraception – even in patients where the probability of persistent fertility is minimal, as in the patient described in this report.
Its application could reduce the necessity for repeated drug administration at frequent intervals due to the sustained release of the formulation, thereby potentially lowering corneal toxicity and increasing patient compliance.
Due to the high costs of the treatment, the side effects and the necessity of repeated treatments every 6 8 weeks, PDT is not considered to be the most optimal treatment for palliation of malignant dysphagia (Lightdale et al, 1995).
