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We identified a remarkably elevated expression of a spectrum of genes involved in Immunity and Defense in PBMCs of RA patients compared to controls.
An in situ hybridization study revealed that MMP-1 expression in normal oral mucosa is controlled at a low level, whereas a remarkably elevated expression level is observed in cases of oral epithelial dysplasia, which becomes even higher in cases of OSCC [ 20].
(33– 35) It was reported that RNF8−/− p53−/− mice had increased levels of genomic instability and a remarkably elevated tumor incidence compared to p53−/− mice, 36) that the knockdown of RNF8 sensitized cells to ionizing radiation, and that disruption of the RING domains of RNF8 impaired DSB-associated ubiquitylation and inhibited retention of 53BP1 and BRCA1 at the DSBs sites.
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In a recent study we found remarkably elevated concentrations of Pb and Zn in the tidemark (TM), which is the mineralization front of human articular cartilage.
Among cellular proteins, LMNA, talin-1, and annexin A1 were remarkably elevated after exposure of PAHs; these may play a role as biomarkers for PAHs exposure.
The Fas, Fas-L and FADD expression levels were remarkably elevated in pM-treated cells when compared to the controls suggesting a possible role of Fas signaling in pM-induced caspase-mediated cell death in these cells (Fig. 4A).
Both, for all the sustained emotional pressure they can achieve, are remarkably "elevated".
Serum liver EPA and DHA levels were remarkably elevated in rats fed FO-enriched MCT or MUFA diets.
Salt stress remarkably elevated the activities of CAT and GPX antioxidant enzymes at vegetative and reproductive stages.
Scopolamine and anisodamine contents were remarkably elevated in the root cultures overexpressing SlH6H/HnH6H, whereas that of hyoscyamine was more or less reduced, when compared with those of the control.
The NO production was remarkably elevated, accompanied by increased mRNA and protein levels of iNOS.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com