Designed substrates allow the ultrahigh sensitive and specific detection of human such biofluids as blood, urine and cerebrospinal fluid (CSF) in a reliable, label-free, and reproducible manner.
On the other hand, the test data from microbial genomes can be expected to be almost free of sequencing errors and the full-length gene annotation should provide a more reliable labelling.
Thus, fusion of an affibody to a FAP should provide a compact and modular affinity probe to instantaneously label pretargeted endogenous protein with simple and reliable labeling protocols using a variety of distinct fluorogen dyes.
The radionuclide 177Lu (Lutetium-177) is being increasingly used in targeted radionuclide therapy (TRT) because of its favorable decay characteristics and the possibility of reliable labeling of biomolecules used for tumor targeting.
However, the progressive availability of neuronal type-specific CreER lines and the combination of genetic tools with serial optic sectioning and newly developed reconstruction methods for imaging (Denk and Horstmann, 2004; Micheva and Smith, 2007) should allow specific and reliable labeling and analysis of additional neuronal types.
Neuronal firing was modulated by the microiontophoretic current for 2 30 min to obtain reliable labeling.
**GFP-TolA was used because the quality of available TolA antiserum was not sufficient for reliable labeling.
Organic remains of otoliths after decalcification for the histological analysis did not allow reliable labeling: the remains were insufficient to reconstruct the otolith contour or were detached from the sensory epithelium through decalcification, dehydration, and embedding procedures.
Therefore, it is reasonable to expect that the FtsZ-mEos2 fusion protein would allow the normal assembly of the Z-ring and serve as a reliable structural label for the Z-ring.
The development of a reliable F-labelling technique together with an automatic synthesis module is a major prerequisite of routine production of F-labelled PET radiopharmaceuticals [ 11– 13].
