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The interrater and intrarater κ-values for reading the intensity of the bands suggested very good agreement, showing that a cutoff of ≥ 2+ could be used as a reliable end point.
Although survival is not a reliable end point for evaluation of efficacy in phase II trials, the median overall survival of 10.0 months in this study compared favourably to ECF (8.7 months), FAMTX (6.1 months), FAMTX (6.7 months), ELF (7.2 months), FUP (7.2 months), and FOLFOX 6 (8.6 months) (Webb et al, 1997; Vanhoefer et al, 2000; Louvet et al, 2002).
Based on the SageGenie algorithm from Boon et al. [ 13] this tag has a high ranking of 95% and is classified as a reliable 3' end of NRGN RefSeq transcripts [NM_001126181] and [NM_006176], which strongly supported the validity of the tag.
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If the application requires a reliable end-to-end connection, the same methodology we have incorporated in this paper shall be used to create a model which accounts for TCP traffic.
To establish a more reliable end-to-end path, an opportunistic routing framework was adopted in [15].
PFS is a more reliable end-point because it reflects the true antitumor benefit of the chemotherapy.
28 Other ITC and MTC meta-analyses on this topic have included both continuous abstinence and point prevalence (an older but less reliable end point) and conducted sensitivity analyses to determine if choice of end point mattered.
Furthermore, creatinine seems not to be a reliable surrogate end point.
"In fact what's happened in the last two weeks is that we've had an unprecedented number of people sign up to attend our workshops, where they can learn to peacefully, reliable end their lives".
Complete follow-up data and reliable end points.
In order to establish which methods, other than mutation screening, might provide reliable end points for determining ATM heterozygosity, we have compared the cellular phenotype before and after exposure to IR of AT heterozygote cell lines with that seen in cell lines carrying a wild type or homozygous mutated ATM gene.
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