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The SAGEmap reliable mapping [ 23] uses a reliability score to classify tag-to-gene associations and tag-to-gene associations with the top two reliability scores are considered reliable.
To minimize false positives in these PPI datasets, we employed as scoring scheme Iterative-CD [ 19] (with 40 iterations) to assign a reliability score (between 0 and 1) to every interaction, and then discarded all low-scoring interactions (< 0.20) to build a dense high-quality PPI network of 29600 interactions among 5824 proteins (average node degree 10.16).
IN its 2008 Car Reliability Study, Consumer Reports ranked the Chrysler Sebring convertible, with a reliability score that was "283 percent worse than average," dead last among the 357 vehicles covered in the survey of subscribers.
The MEPISA yielded a S/CVI = 0.72 and a reliability score of 0.73.
All studies were assigned a reliability score according to Klimisch et al. [54].
As the NASA team describes in a paper published today in The Astrophysical Journal, when they applied the technique to their nearly 4700 candidates, they found 1284 with a reliability score greater than 99%.
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Similarly, 2,729 genes had a reliability-score between 10 and 70, while 1555 showed a score of 4 or less.
Of the 8,410 genes, 674 had a reliability-score greater than 70, indicating that they have a higher probability of being expressed in human testicular cancer conditions.
And, it will be useful to 'predict' expression patterns of genes, using a reliability-score such as the one reported here.
For example, a gene reported to be 'not detected' in normal rat testis by two studies, would be shown as 'dormant' in normal rat testis with a reliability-score of four.
Next, we removed for further analysis all expression values for a given probe set with a poor reliability score or 'A' call (ambiguous signal) that occurred across all samples.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com