Exact(1)
Thus, in the current study, we have compared responses in VSM and macrophages to specific ligands for TLR4 and NOD1, and measured NOS2 activity as a relevant readout of cell activation.
Similar(59)
In the development of cancer vaccines, a direct testing of cytolytic activity, as provided by our arrays, represents the most relevant readout.
In addition, even though neurite length and complexity may be relevant readouts for the cellular effects of LRRK2, enhanced stress sensitivity and cell death are equally informative for our understanding of LRRK2 function in cultured cells (55).
Although, evaluation of inflammation and pain have been previously reported in other preclinical models of arthritis [ 40– 42], to our knowledge, this is the first report investigating the clinically relevant readouts such as pain and inflammation simultaneously in the SCW model.
However, when a GIM is overlapping such a locus, then, due to its generally much stronger effect size and its more direct link to the genetic variant, this GIM can provide intermediate and functionally relevant readouts (5) that allow for the identification of multiple causal variants in order to satisfy the criteria lain out by Plenge et al. (57).
In order to achieve high-throughput screening of HIV PIs in a relevant setting with a high readout, we have produced a stable T-cell line that can be used as a sensitive indicator of HIV-1 PR activity.
We would select information available in pathway databases and a relevant transcriptomics and/or proteomics experimental dataset (typically readouts after various perturbations), and then put CellNOptR to work.
A relevant fraction of the electric-field streamlines, generated by the readout voltage applied between the electrodes, develops in the air (or vacuum) volume over the electrodes.
Since mRNA expression is an important readout of underlying genetic and epigenetic signatures, we attempted to identify which leukocyte population might be a relevant cell target for ORMDL3.
Here's a relevant talk:.
(Here's a relevant paper).
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