The finding that both KI67 and p53 are over-expressed in a relevant fraction of our patients exhibiting poor outcome is in agreement with numerous published studies attributing to the above proteins a role as predictors of adverse prognosis in several human tumour types, including head and neck cancers.
As many masonry domes, the dome of the Basilica of S. Maria Assunta in Carignano in Genoa, designed by Galeazzo Alessi and built in the XVIth century, exhibits a relevant crack pattern, consisting mainly of meridian cracks, which puts forward the issue of its safety.
This exhibit is just one of Philbrook's recent initiatives to establish itself as a relevant destination for 20th century design.
There was an exhibit of the Metropolitan Daily Institute.
Furthermore, patients exhibited a clinically relevant degree of chronic stress as well as signs of depression.
In these cell lines, which exhibited a biologically relevant degree of resistance, both transporters were found to localise in the trans-Golgi network in the absence of cisplatin.
Thirdly, the biologically relevant complexes exhibit a remarkable redundancy of observation wherein the presence of ligand is observed in every monomer.
Fourth, Wnt3a liposomes exhibit robust activity in a biologically relevant model of hair follicle neogenesis.
A significant underlying assumption of these proposals is that the intracellular and secreted ADAMTS13 (which is physiologically relevant) both exhibit proteolytic activities.
In addition, our previous studies showed that clinically relevant concentrations of propofol exhibit broad-spectrum inhibition of hepatic and renal monooxygenase activities and enflurane defluorination [ 20, 21].
Individuals with a history of unipolar depression (whether with or without clinically relevant symptoms of depression) exhibited shorter telomeres in the three analyzed leukocyte subsets (CD4+ T helper cells, CD8+ cytotoxic T cells, and CD20+ B cells).
