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On the other hand, if such overestimation occurs during the outbreak, a lower peak incidence (and thus a lower burden for health care centers) and a relevant decline of the final epidemic size would be observed.
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Mental decline was defined as a relevant decline in any of these tests between T0 and T1.
Physical decline was defined as a relevant decline in any of these tests between T0 and T1.
The early initial prodromal state was operationally defined by either basic symptoms predicting psychosis [ 10] or by a clinically relevant decline of functioning in combination with established risk factors (risk and decreased functioning) [ 22].
In patients whose Framingham risk score was calculated by chart or formulae, 22.2% of patients registered a relevant decline in total cholesterol.
Although not statistically significant, the proportion of cancer patients who experienced a relevant decline in QoL was smaller compared to persons without cancer.
Cognitive testing revealed clinically relevant decline of performance in no test for 10 (28.5%), in one test for 10 (28.5%), in two tests for 6 (17%), in three tests for 7 (20%) and four tests in 2 patients (6%).
Accurate and timely assessment of a clinically relevant decline in respiratory status is crucial for determining the timing of feeding tube placement, as much if not more so than an accurate assessment of swallowing ability.
In the present study, almost 16% of a community-based sample of older patients with type 2 diabetes experienced a clinically relevant decline in cognitive function after 1.6 years of follow-up.
The relevant decline was determined as a shift of score from <5 to ≥5 [ 41].
A relevant PSA decline was detected in 70%% of patients.
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