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Of note, fenretinide is currently studied for a phase II trial in HR-NB patients following a successful phase I trial and recent pharmacokinetics studies conducted in NB patients indicated that a continuous oral administration of 4-HPR is preferred to maintain a relevant and efficient plasma concentration of 0.7 -10 μM range [19, 51)].
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Recent results on follicular penetration emphasize that the hair follicles represent a highly relevant and efficient penetration pathway and reservoir for topically applied substances. 1 Hair follicles are an interesting target site for topical applications.
It lists a series of reforms needed to keep the body relevant and efficient, including extending the scope of its oversight, allowing flexibility in taking common action, and revisiting the developing-developed country classification.
This results in a comprehension on the site-specific effectiveness of solar DEC-systems and provides insights on principally relevant and efficient system configurations.
Consequently, they are strongly dependent on their collaborative processes and matching workflows, which have to be relevant and efficient through time.
Selecting relevant and efficient abatement options.
In order to continue and be relevant and efficient, the movement must be revamped and reshaped.
The body again says it's generally happy with these criteria — saying they "all appear to be relevant and efficient in the context of delisting requests".
The process itself would be reviewed at the same time to ensure that it is relevant and efficient.
Silencing of miRNAs might be therapeutically relevant and efficient in vivo silencing in rodents and nonhuman primates with chemically modified antisense nucleotides has been proven successful in the treatment of cancer and hepatitis C infection [ 13, 14].
Since they offer a biologically relevant and computationally efficient formalism for analyzing the relationship between molecular network topology and function, BNs have been used extensively to simulate the behavior of cells based on their network activity.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com