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This phenomenon has been attributed to a release from constraints on form and function driven by the high ratio of O2 supply to metabolic demand for these organisms [37], [38]; [ but see 39].
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His father, Auberon, enjoined upon him a certain anarchic stoicism, obviously derived from his own father, about the vicious floggings that both endured at their monastic schools: "The monks enjoyed whipping boys as a release from the constraints of their celibacy, and my father, throughout his life, always claimed that to be beaten was a small sacrifice for a boy and a great treat for a monk".
Such a release from epistastic constraints has been observed for HIV adapting to two different T-cell lines, where adaptation in one cell environment led to a higher fitness in the alternative than in the selective cell environment (van Opijnen et al. 2007).
Where the homology is the result of speciation so that the history of the gene reflects the history of the species…the genes should be called orthologous (ortho = exact).' Duplication events provide a release from evolutionary constraints, allowing genes to explore novel functions [ 28].
Instead these data suggest a release from evolutionary constraint model, followed by aquatic diversifications within crown families.
Grouping therefore leads to a release from individual sensing constraints and a shift in niche specialization, allowing individuals to better exploit partially depleted patches.
The hypothesis posits that a number of innovations to the vascular system provided the release from constraints which allowed the implementation of an AIS.
Whether this difference is due to a release from neurogenesis-based developmental scaling constraints, or due to a strong adaptive requirement for enhanced olfaction, remains to be established.
These innovations provided the evolutionary release from constraints that allowed the implementation of an AIS: whereas adipocytes buffer against the sudden metabolic demand associated with the activation of an AIS, vascular innovations decreased the cost of mobilising an antibody-based immune response and augmented the performance of an AIS (e.g., promoting affinity maturation).
Also, since it is argued that the closed vascular system provided the release from constraint, a number of vascular innovations must have preceded the advent of an AIS.
(a) Release from 3 4 km.
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Justyna Jupowicz-Kozak
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