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Among 91 hepatitis E cases, acute marker profiles of 82 cases are compatible with primary infection, reflecting a vigorous IgM response, a relatively weak and transient IgG response with production of low avidity IgG and a relatively protracted viremia.
Our findings add to a body of literature showing a relatively protracted development of sensitivity to coherent motion (Gunn et al., 2002; Hadad et al., 2011).
Coupled with the fact that such mutations were observed at several discrete levels of ploidy, these data suggest that the genomic rearrangements driving the amplifications in these patients were acquired over a relatively protracted period of molecular time.
By contrast, epiSCs with Klf2 alone produced GFP-positive cells but in a relatively protracted manner on day 6 7, and more robustly on day 9, compared to a highly accelerated rate of reprogramming by Prdm14 and Klf2.
As noted previously (e.g., Palmer et al., 2007; Koenig et al., 2011; Yatsunenko et al., 2012), the development of the gut microbiota involves profound alterations in diversity and composition that take place over a relatively protracted timeframe (nominally, 0 3 years in age) (Table 2 and Figure 2).
We also noticed a difference in the kinetics of primed to naive conversion using previously reported protocols: whereas the emergence of naive colonies under our conditions is a relatively protracted process (ca. 10 days) that occurs after widespread cell death, the application of previously described naive conditions was accompanied with little cell death and rapid expansion of the cells.
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First, the overall magnitude of % BOLD signal change across the entire timecourse tended to be lower in the CO/DA+ regions than the FP regions, supporting a role for the CO/DA+ regions in reading out a bias signal (relatively rapid), and a role for the FP regions in accumulating information over time in order to make a decision (relatively protracted).
Of particular interest were the general response properties characterizing a region (relatively rapid vs. relatively protracted); the difference between words and pseudowords in each task for each region; the difference between regular and irregular words in each task for each region; and the anatomical locations of the regions that are most functionally similar to the candidate regions.
If spatial decisions are indeed made within an intersection, then it may be suitable to dynamically cue navigation guidance when a pedestrian enters an intersection; however, if spatial decision-making is relatively protracted and precedes the entrance to an intersection, it may prove advantageous to cue guidance in anticipation of upcoming intersections.
The reconstructed body sizes of all subfossil lemurs are substantially larger than those of their extant relatives (Jungers et al. 2008), and dental histology patterns suggest that ages of weaning and interbirth intervals for many of these taxa were relatively protracted as well (Catlett et al. 2010).
Tuned percussion adds a suitably exotic element, but this relatively protracted voyage needed a faster following wind.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com