Sentence examples for a regulated functional from inspiring English sources
A number of peptide hormones, such as those in secretory granules of the endocrine system, have been found to aggregate into amyloids in secretory pathways in a regulated, functional manner [50], [51], so there is a possibility that myostatin aggregates are protective in the sIBM diseased state.
The analysis of the down regulated functional groups pointed out towards redox/detoxification processes affected in both tissues and mitochondrial functions observed in liver tissue.
Still, the same trend in regulated functional groups was observed.
We evaluated the effect of lupeol on STAT3 signalling cascade and its regulated functional responses in HCC cells.
In invertebrates, genes belonging to dynamically regulated functional categories appear to be less methylated than "housekeeping" genes, suggesting that DNA methylation may modulate gene expression plasticity.
Annotation analysis was performed to identify the regulated functional groups via Gene Ontology classifications using GOrilla and REViGO web applications (Geiss et al., 2008).
Other down regulated functional categories include physiological defense (11%), metabolism (8%), lipid metabolism (7%), transport (4%), translation (4%) and other (17%).
The example we presented here can also be used as an outline that guides researchers through microarray analysis with the aim of identifying regulated functional categories of genes in plants.
Analyses of gene expression data from microarray experiments has become a central tool for identifying co-regulated, functional gene modules.
After genes with unknown function were discounted, a specific distribution of up- and down-regulated functional categories was observed in the various clusters.
Thus, up-regulated genes upon paclitaxel exposure are implicated in apoptosis, cell adhesion and cytoskeleton structure (including a number of tubulin genes), while down-regulated functional groups comprised genes linked to cell growth and proliferation, immune response and transcription regulation.
