This paper discusses the application and evaluation of this apparatus, performed with several generic and reference batches of immediate release tablets containing atorvastatin (ATV).
References in the dataset are grouped by the reference batch size (RBS) of 32 in this test.
Moreover, other two tests were performed to investigate the impact of different reference batch sizes (RBSs) on GPU performance in Tables 4 and 5, where 256 and 32 queries were used, respectively.
The working group organized in the Generic Committee focusing on itraconazole found batch-to-batch variations in dissolution profiles of the originator capsule product, which suggested possible differences in the performance of reference batches for the development of generic products.
AF4 of GP2013 and reference batches was performed using a liquid chromatography system equipped with a UV detector from Agilent (Boeblingen, Germany) and a light-scattering and refractive detector from Wyatt (Santa Barbara, CA, USA).
Intact mass: The molecular masses of the GP2013 and reference batches were determined using a Q-TOF mass spectrometer (Synapt®, Waters, Saint Quentin en Yvelines, France) after the heavy chain C-terminal lysine had been enzymatically removed.
Bootstrap of f2 generates a new population of dissolution profiles through random samples with replacement from 12 units of the test and reference batches, respectively [ 28, 29].
Instead, NVIDIA is making the Tegra Note reference design available to a global batch of OEMs and partners who want to run with it, meaning there's a decent chance that the no-name tablet you uncle picks up a few months down the road will actually sport a bit of NVIDIA lineage.
The further tested buffered formulations included two reference batches from the BE studies (Lipitor and Sortis10), plus one other batch of the reference product, Sortis06.
