The phrase "a reduction of function" is correct and usable in written English.
It can be used in contexts discussing a decrease in the capability or performance of a system, process, or biological function.
Example: "The patient experienced a reduction of function in their mobility after the surgery."
Alternatives: "a decline in function" or "a decrease in capability".
In C. elegans it has been reported that worms with a reduction of function of an NPY-like receptor, NPR-1, phenocopy ethanol withdrawal [17].
In the case of glp-1 e2141) glp-1 e2141reduction of function of either danimalsr aak-2 alone did not significantly reductione viability of unimpaired phenotype afunctionee days of anoxia treithert.
Twenty-eight of the mutations we used are presumptive null alleles characterized by small deletions or nonsense substitutions, whereas the other two mutations were previously reported to cause a reduction of function.
The animals grow slowly, and have decreased fat stores and altered fatty acid composition compared to wild type (Figures S1B and S1C), indicating that this deletion is a reduction-of-function allele [7], [17], [18], [24].
This result is consistent with the idea that eat-6 ad467 eat-6 ad467tisn-of-function mutation [10] and suggests that a low dosage of the WT gene, in contrast to a high dosage introduced by an extrachromosomal array, can correct aldicarb sensitivity of the ad467 mutation
The biopterin regeneration mutants showed clear effects on neurotransmitter synthesis when combined with a reduction-of-function cat-4 mutation.
(A ) Cartoon illustrating a previously established enhancer assay using a reduction-of-function (rf ) ced-3 allele (Reddien et al., 2007 ).
We identify CD44 expression as a sensitive reporter of tonic mTOR-S6 kinase signaling through a novel mouse strain, chino, with a reduction-of-function mutation in Mtor.
After completing the RNAi screen, we tested several point mutations in Y55F3AM.3 generated by the Million Mutation Project (Thompson et al. 2013) to identify a reduction-of-function allele.
age-1(hx546) animals, which have a reduction-of-function point mutation in the age-1 gene, exhibit a 40-11040-110%sion in mean lifespan, and higher tolerance to thermal stress [ 12, 14, 15, 34, 95].
We next tested a gain-of-function mutation in the downstream kinase akt-1 [ 22] and a reduction-of-function mutation in daf-18 [ 23], the PIP3 3-phosphatase PTEN.
