The phrase "a reduction in transcript" is correct and usable in written English.
It can be used in contexts related to academic or medical settings, where it refers to a decrease in the amount or quality of a transcript, such as a record of academic performance or a written account of spoken words.
Example: "The study showed a significant reduction in transcript levels of the targeted gene after treatment."
Alternatives: "a decrease in transcript" or "a decline in transcript".
However, it is simple to determine if the late stage reduction in GFP translated from the GFP-312 mRNA is accompanied by a reduction in transcript levels.
Thus, according to the selection for energy cost hypothesis, highly expressed genes are likely to experience greater selective pressure for a reduction in transcript length [1].
The transcript denoted as R3 increased in abundance through growth in a manner similar to the observed expression profile of the sRNA MicA [25]; it increases monotonically, peaking in mid stationary phase prior to a reduction in transcript intensity through late stationary phase.
Two mechanisms may lead to cardiomyopathy inactivation of an allele (a null allele), leading to a reduction in transcript and functional protein (haploinsufficiency); or production of a mutant protein ("poison peptide") which interferes with normal function (dominant negative) or assumes a new function.
In both transgenic lines we observed a reduction in transcript accumulation of the genes evaluated, with the exception of AOX1A.
Overexpression of atwhy2 in Arabidopsis compromised mitochondrial function by causing a reduction in transcript levels and mtDNA content.
However, another mechanism may be suggested in our transcript profiling data, which illustrates a reduction in transcripts associated with terpenoid biosynthesis, which lies upstream of ergosterol production.
Quantitative expression analysis demon-strates a reduction in transcripts for both Sur and the inward rectifying potassium channel (Kir) subunits when IPCs are partially ablated.
Poly-adenylation events cause a reduction in the transcript size, blocking the transcription of portions of its 3' region, together with the most 3' restriction site of the enzyme used for constructing the SAGE library.
Immunohistochemistry demonstration of reduced synovial B-cell expression was confirmed by a reduction in CD19 transcript levels (data not shown) although IgM transcript levels were unchanged.
A reduction in CD19 transcript levels was consistent with the immunohistochemistry findings; interestingly, IgM transcripts did not change, suggesting the B-cell effect is different to that noted with anti-CD20 both in magnitude and character.
