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In liver, FGF21 in the MAPK signaling pathway decreases on the expression of IGF-1 via a reduction in concentrations of the active form of STAT5 [ 20].
5 In addition, several meta-analyses of observational studies and randomized controlled trials have found that a reduction in concentrations of LDL cholesterol could significantly reduce the risk of coronary heart disease and stroke incidence and mortality.
The results of the pilot showed a non-significant trend for a reduction in concentrations of T-tau in neat CSF and no evidence of a reduction following the addition of Tween 20.
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All compounds showed a reduction in concentration of 89% to 100%, independent of high- or low-start concentration.
A reduction in concentration of N and Al is observed with increasing substrate biases.
In the buffer fraction, an increase in the concentration of a metabolite indicates efflux from the mitochondrial fraction, whereas a reduction in concentration indicates mitochondrial uptake.
Because these compounds are lipophilic, increasing fat mass results in an increase in volume of distribution and a reduction in concentration, even in the absence of any elimination.
The greater cellulose and lignin concentrations in stems of genotype 252 compared to genotype1282 are associated with an 11% increase in total cell wall dry matter and a reduction in concentration of pectin sugar residues in the cell wall.
A long-term remediation strategy would therefore be evaluated based on a reduction in concentration of sediment contaminants and a return to community abundance that reflects a less-contaminated state.
"The long-term goal," its report said, "needs to be a reduction in the concentrations".
Repeated use of some frying pans was observed to result in a reduction in PFOA concentrations emitted in the gas phase.
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