Sentence examples for a reduced threshold for from inspiring English sources

This observation is in agreement with the [Ca2+]o-dependent SOICR activity described above, indicating that a substantial SOICR activity, as observed with HEK293 cells expressing the former RyR2 variants, is accompanied with a reduced steady-state Ca2+ loading of the internal store and a reduced threshold for SOICR.

HD patients of the "frail" phenotype are likely to be most at risk of harm from IDH because of their reduced coronary flow reserve, and therefore to have a reduced threshold for developing myocardial ischemia in the setting of reduced coronary perfusion pressure [ 17- 22].

Furthermore, FHM1 KI mice have shown a reduced threshold for CSD induction and an increased velocity of CSD propagation [63, 104].

This might be related to a reduced threshold for triggering CSD in patients with epilepsy in comparison to patients without epilepsy.

This could be through orbital venous plexus congestion during effort in the presence of jugular venous incompetence and a reduced threshold for trigeminal sensory activation.

Primary cough headache appears to be caused by a congestion of the orbital venous plexus in the presence of jugular venous incompetence and a reduced threshold for trigeminal sensory activation.

A first analysis was performed according to the recommendations of Affymetrix, but with a reduced threshold (0.90) for the variant call frequency instead of the default value (0.97) to account for the high amount of PAVs in the maize genome [ 17].

Furthermore, when considering disruption to the local interactome PIK3R1 was highly ranked, suggesting a greatly reduced threshold for signalling through PI3K, particularly under conditions where HPX is driving EMT.

In the present study, electrophysiological extracellular hippocampal recordings in vitro reveal that conditional loss of Cdk5 also leads to elevations in fEPSPs with a predominant NMDA component and reduced threshold for population-spike activity.

In 2002, Batelli et al. reported also hyperexcitability of the extrastriate cortex V5 (an area particularly devoted to visual perception of motion) showing reduced threshold for the induction of "moving phosphenes", particular phosphenes that are perceived to move in the visual field [32].

In addition, TP53 inhibits autophagy [205], resulting in impaired mitophagy, contributing to the reduced threshold for cell death.