Chamberlain, J. S., Metzger, J., Reyes, M., Townsend, D. & Faulkner, J. A. Dystrophin-deficient mdx mice display a reduced life span and are susceptible to spontaneous rhabdomyosarcoma.
However, long-term in vitro culture of hBMMSCs leads to a reduced life span of the cells due to senescence, which leads eventually to growth arrest.
Mice that were homozygous for the mutation had a reduced life span.
Too much deformation can permanently change the size of the object leading to undesired gaps between the object and the pipe/tube, or can deteriorate the object leading to a reduced life span.
These diseases share the common symptoms of skeletal muscle degeneration, cardiomyopathy, as well as a reduced life span for afflicted individuals [3].
Figure 1B shows that although elt-2 RNAi animals exhibit a reduced life span compared to control animals, they survive at least eight days, indicating that starvation is not a cause of death.
The impact of the APOE polymorphism on the increased risk of a variety of medical illnesses might lead to a reduced life span and decreased adaptability of affected individuals to stress.
Since CL2070 worms were more vulnerable to heat stress and showed a reduced life span compared to Luc GFP and N2 worms we adapted the experimental conditions for this strain to 32°C heat stress and 10 days of adulthood for aged worms.
Inattention was described as a lack of attention or a reduced attention span.
These mice, which displayed defective apoptosis, had a reduced life span and most developed tumors.
It can be concluded, therefore, that PES is not responsible for a reduced life span.
