Besides, thiol-CysDs had a reduced activity in acidic pH (5.0).
If expression (4) gives a value of more than 250 MBq, then the acquisition time is increased to 4 min per bed position and a reduced activity administered is calculated using expression (6).
The C33 isoform has a reduced activity and no tendency towards saturation was observed up to 200 µM of SAM leading to a 15-fold increase in the Km value compared to CsACS2 isoform (Figure 4, Table 2).
PT7 had a reduced activity in flowere than PT6.
Specimens kept under sterile conditions to allow the mycelium to recover from injury showed a reduced activity.
The valine variant was reported to have a reduced activity when recombinantly expressed in Escherichia coli (Zimniak et al, 1994).
Furthermore, in agreement with Fig. 6b, Bio-NHS-TRAIL showed a reduced activity as compared to unmodified TRAIL, while Bio-ULS-TRAIL retained its activity.
Previous works show that when mutated, cysteine proteinase 5 (CP5) has a reduced activity and the trophozoite has a reduced ability to generate ALA [ 26].
The results showed that QOL decreased according to activity limitations, suggesting that a reduced activity level is associated with decreased QOL.
The release of CO2 from [1-C]-glucose is furthermore consistent with a reduced flux through the TCA cycle, but could also suggest a reduced activity of the oxidative pentose phosphate pathway (OPPP).
Hence, we suggested that low plasma carnitine concentrations are caused by a reduced carnitine synthesis due to a reduced activity of iron-dependent enzymes involved in carnitine synthesis.
