Loss of function of the cohesin complex is incompatible with life; however, mutations in the genes encoding for cohesin subunits and/or cohesin cofactors, which have very little or a null effect on chromosome segregation, represent a newly recognized class of human genetic disorders known as cohesinopathies.
They represent a newly recognized class of DNA variation, identified as a result of the introduction of comparative genomic hybridization (CGH) array technology that enables the study of variation in the number of copies of specific DNA segments among individuals [ 4, 5].
The current paper presents a model for diseases of abnormal polymerization (DAPs), as a newly recognized class of disorders.
In a packed Pauley Ballroom, a crowd of some 800 was rapt as the speakers detailed science's successes in tackling heart disease, the challenges still facing medicine with regard to cancer, and the intriguing novelty of a newly recognized class of disease — prion diseases.
In terms of the representation of the ten (A-J) recognized classes of Sox genes, our studies confirm the presence of group B, C, E and F Sox types in cnidarians, and are consistent with the absence of group D, G, H, and I as reported by Magie et al. [ 9].
A more recently recognized class of environmental contaminant, whose chemical structure is similar to PCBs, is the brominated flame retardants, which includes the polybrominated diphenyl ether (PBDE) congeners (Gill et al. 2004; Hites 2004).
Long noncoding RNAs (lncRNAs) are a pervasive and recently recognized class of genes.
The D2R and D3R peptides were the most clearly recognized class A filamin binders.
The other half, the ones in the newly recognized class, are closer to Earth, a few hundred light-years away.
Poly amidoamine) dendrimers are the most recognized class of dendrimer.
There are four recognized class generations of cephalosporins based on their activity spectrum.
